| Pharmacokinetics Parameter |
TEST |
REF |
| Cmax (μg/ml) |
2.88 ± 0.09 |
3.03 ± 0.09 |
| Tmax |
2.22 ± 0.04 |
2.24 ± 0.03 |
| t1/2 |
1.35 ± 0.25 |
1.35 ± 0.19 |
| AUC0-t (mg/L.hr) |
9.60 ± 0.38 |
10.23 ± 0.44 |
| AUC0-∞ (mg/L.hr) |
10.75 ± 0.47 |
11.42 ± 0.46 |
| AUMC (mg/L.(hr)2 |
32.42 ± 3.68 |
36.51 ± 7.14 |
| Relative Bioavailability (% F) |
93.89 |
| Kel (hr-1) |
0.52 ± 0.10 |
0.52 ± 0.07 |
| Vd (L) |
49.05 ± 8.27 |
46.00 ± 7.15 |
| CL (L/hr) |
25.13 ± 1.13 |
23.50 ± 1.26 |
| MRT (hr.) |
4.21 ± 0.25 |
4.18 ± 0.25 |
|
