| |
Geometric mean |
|
|
| Parameter (Units) |
Reference (linezolid tablet), N=20 |
Test (linezolid oral suspension), N=20 |
Ratio* (%) |
90% CI for ratio (%) |
| AUCinf (µg*h/mL) |
109.8 |
107.2 |
97.65 |
92.92-102.63 |
| AUClast (µg*h/mL) |
109.3 |
106.9 |
97.81 |
93.11-102.75 |
| Cmax (µg/mL) |
13.3 |
15.2 |
113.67 |
105.26-122.75 |
AUCinf, area under plasma concentration–time curve from time zero extrapolated
to infinite time; AUClast, area under plasma concentration–time curve from time
zero to the time of the last quantifiable concentration; CI: Confidence Interval; Cmax,
maximum plasma concentration; CV, Coefficient of Variation.
*Ratio of adjusted geometric mean for Test treatment (linezolid 600 mg oral
suspension) versus Reference treatment (linezolid 600 mg tablet). |
