| Parameter |
Condition |
Mean peak area ± SD (% RSD) |
% Assay |
Theoretical plates |
| Rosuvastatin |
| Flow rate (ml/min) |
0.9 |
3557208.67 ± 8898.09 (0.25) |
99.85 |
|
| 1.0 |
8134 |
| 1.1 |
|
| Detection wavelength (nm) |
252 |
3551673.00 ± 16076 (0.45) |
99.69 |
|
| 254 |
8530 |
| 256 |
|
| Mobile phase composition (v/v) |
34:66 |
3532385.67 ± 26472.49 (0.75) |
99.15 |
|
| 32:68 |
8457 |
| 30:70 |
|
| pH |
3.3 |
3551673.67 ± 38794 (1.09) |
99.69 |
|
| 3.4 |
8265 |
| 3.5 |
|
| Ezetimibe |
| Flow rate (ml/min) |
0.9 |
4346140.00 ± 8730.76 (0.20) |
99.78 |
|
| 1.0 |
10986 |
| 1.1 |
|
| Detection wavelength (nm) |
252 |
4359196.67 ± 11949.63 (0.27) |
100.08 |
|
| 254 |
10859 |
| 256 |
|
| Mobile phase composition (v/v) |
34:66 |
4318080.67 ± 36416.96 (0.84) |
99.13 |
|
| 32:68 |
10945 |
| 30:70 |
|
| pH |
3.3 |
4325117.33 ± 30964.03 (0.72) |
99.30 |
|
| 3.4 |
10674 |
| 3.5 |
|
