Formulation Parameters Test Product Reference Product
Trimetazidine Cmaxss (ng /mL) 95.263 ± 20.773 90.794 ± 23.973
Cminss(ng /mL) 36.842 ±12.222 34.376 ± 15.102
AUCTau( ng.hr/mL) 772.445 ± 200.860 725.606 ± 201.223
Fluctuation % 94.697 ± 25.857 98.289 ± 40.257
Note: Data are shown as least square mean ± standard deviation for pharmacokinetic parameters.
Abbreviations: AUCTau, area under curve at steady state; Cmaxss, peak concentration at steady state; Cminss, minimum concentration at steady state
Table 2: Mean Pharmacokinetic Parameters of Trimetazidine at steady state.
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