HDACI Study Phase Identifier Number
Entinostat (SNDX-275) Azacitidine and Entinostat in Treating Patients With Advanced Breast Cancer II NCT01349959
Entinostat Exemestane With or Without Entinostat in Treating Postmenopausal Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic III NCT02115282
Entinostat Entinostat, LapatinibDitosylate and Trastuzumab in Patients With Locally Recurrent or Distant Relapsed Metastatic Breast Cancer Previously Treated With Trastuzumab Only I NCT01434303
Panobinostat (LBH589) Re-expression of Estrogen Receptor (ER) in Triple Negative Breast Cancers I/II NCT01194908
Vorinostat Vorinostat in Treating Patients With Stage IV Breast Cancer Receiving Hormone Therapy Pilot NCT01720602
Vorinostat Vorinostat, Paclitaxel, and Bevacizumab in Treating Patients With Metastatic Breast Cancer and/or Breast Cancer That Has Recurred in the Chest Wall and Cannot be Removed by Surgery I/II NCT00368875
Vorinostat Ixabepilone and Vorinostat in Treating Patients With Metastatic Breast Cancer I NCT01084057
Table 1: Examples of some clinical trials of combination therapies using HDACIs in breast cancers (obtained from www.ClinicalTrials.gov in May 2014) [24].
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