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| Figure 1: Interrelations and biological functions of major physiological ROS. NADPH, nicotinamide adenine dinucleotide phosphate (reduced form); SOD, superoxide dismutase; NO●, nitric oxide; ONOO-, peroxynitrite; SRP, standard reduction potential; O2 ●-, superoxide; H2O2, hydrogen peroxide; Mn+, redox active metal ion; ●OH, hydroxyl radical; MPO, myeloperoxidase; HOCl, hypochlorous acid; Prx, peroxiredoxin; PTP, protein tyrosine phosphatase; TF, transcription factor. See the text for details |
