| |
Test, Microser ® |
Reference, Serc ® |
| 24 mg Betahistine |
24 mg Betahistine |
| Cmax |
tmax |
t½ |
ABCt |
ABC∞ |
MRT |
Cmax |
tmax |
t½ |
ABCt |
ABC∞ |
MRT |
| (ng/mL) |
(h) |
(h) |
( ng*h/mL) |
(ng*h/mL) |
(h) |
(ng/mL) |
(h) |
(h) |
(ng*h/mL) |
(ng*h/mL) |
(h) |
| Mean |
1716.2 |
0.9 |
3.7 |
7139.8 |
7660.2 |
4.6 |
1677.3 |
0.9 |
3.3 |
6714.4 |
6850.3 |
4.6 |
| St Dev |
307.5 |
0.3 |
3.1 |
2284.3 |
4636.9 |
1.3 |
252.6 |
0.3 |
1.3 |
1413.2 |
1622.8 |
1.1 |
| St Error |
54.4 |
0.0 |
0.6 |
403.8 |
819.7 |
0.2 |
44.7 |
0.1 |
0.2 |
249.8 |
286.9 |
0.2 |
| CV |
17.9 |
30.6 |
84.3 |
32.0 |
60.5 |
28.6 |
15.1 |
38.3 |
38.1 |
21.0 |
23.7 |
24.2 |
| Median |
1772.8 |
0.8 |
3.3 |
6971.8 |
7081.4 |
4.5 |
1742.5 |
0.8 |
3.3 |
6363.6 |
6427.7 |
4.5 |
MRT= Mean residence time; St Dev = Standard deviation; St Error = Standard error; CV = Coefficient of variation expressed as percent |
