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| Figure 5: Comparison of the anti-proliferative effect of SCFA synthetic formulations (SSFs) with the anti-proliferative effect of L. reuteri-CM. This evaluation was performed to study if L. reuteri –CM owe, totally or partially, their effect in suppressing colon cancer cells to the levels of naturally produced SCFAs they contained? The quantities of chemical compounds in the synthetic formulations are the same as naturally produced by L. reuteri bacteria (L. reuteri NCIMB -11951, -701089, -701359, -702655, and 702656) in CM, as presented in Table 1. L. acidophilus ATCC 314 is used as a positive control and for comparative purposes. Data are represented as mean ± SEM (n = 5). *p <0.05 and ***p <0.001, compared with untreated groups. |
