Pharmacokinetic parameter
Flogofin
®
(Test)
Profenid
®
(Reference)
AUC
0-24
([μg h]/mL)
52.21 ± 1.15
50.68 ± 10.52
AUC
0-±
([μg h]/mL)
52.38 ± 11.51
50.84 ± 10.57
C
max
(μg/mL)
21.58 ± 6.69
21.65 ± 8.48
T
max
(h)
1.10 ± 0.53
1.49 ± 1.00
T
1/2
(h)
3.62 ± 0.75
3.54 ± 0.59
K
e
(h
-1
)
0.20 ± 0.05
0.20 ± 0.05
Table 1:
Pharmacokinetic parameters obtained from 24 volunteers after oral administration of 200 mg ketoprofen (4 capsules x 50 mg) formulation (Mean ± Standard deviation).
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