Probability of Exceeding
Limits of Acceptance
Ratio,
Parameter
%Reference
90%CI
<80%
>125%
Ln C
max
% ratio
102.4
89.3-117.5
<0.00268
<0.01039
Ln AUC
0–t
% ratio
103.1
98.1-108.4
<0.00000
<0.00000
Ln AUC
0–∞
% ratio
103.2
98.2-108.4
<0.00000
<0.00000
Table 2:
Comparison of 90% CIs of natural log-transformed ratios of C
max
, ln AUC
0– 24
, and ln AUC
0–∞
, the probability of exceeding the limits of acceptance, and power test in KPF capsules (4 capsules × 50 mg).
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