unless stated otherwise

	*Paracetamol*		*Ibuprofen*
	*Maxigesic® – fed*	*Maxigesic®– fasted*	*Maxigesic®– fed*	*Maxigesic®– fasted*
C_max (µg·mL^-1)	12.94	13.89	20.39	21.48
Geometric mean ratio [%], (90% CI)	89.32 (76.37 – 104.47)		94.96 (86.56 – 104.18)^b
AUC_0-t (µg·mL^-1·h)	38.11	38.32	70.25	80.12
Geometric mean ratio [%], (90% CI)	99.42 (95.89 – 103.08)^b		88.41 (85.47 – 91.43)^b
AUC_0-inf (µg·mL^-1·h)	40.80	40.47	72.20	82.30
Geometric mean ratio [%], (90% CI)	100.78 (97.19 – 104.48)^b		88.40 (85.80 – 91.07)^b
T_max (minutes)^a	53	30	53	90
T_1/2 (h)	3.47	3.14	2.08	2.12

^amedian ^bwithin bioequivalence limits (80%-125%)

Table 3: Comparison of the geometric mean (unless stated otherwise) pharmacokinetic parameters of paracetamol and ibuprofen after administration as Maxigesic® in fed and fasted states.

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