Parameter
Capsule
Solution
C
max
(ng/ml)
340.335 ± 23.182
352.737 ± 21.651
t
max
(h)
4.310 ± 0.485
4.227 ± 0.250
AUC
last
(ng.h/ml)
3745.386 ± 350.886
3535.320 ± 235.311
AUC
∞
(ng.h/ml)
3967.991 ± 362.317
3911.227 ± 249.533
t
1/2
(h)
6.793 ± 0.452
6.682 ± 0.490
Table 1:
Pharmacokinetic parameters of oseltamivir carboxylate (OC) observed in 22 Mexican healthy volunteers after administration of a single 75 mg dose as oseltamivir capsules or non-commercial solution. Data are presented as mean ± SEM.
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