Ingredients Amount (mg / tablet)
FM1 FM2 FM3 FM4 FM5
Microcrystalline cellulose (Avicel pH 102) 150 150 150 150 150
Di basic calcium Phosphate dihydrate (DBP) 150 150 150 150 150
Lactose anhydrous 124 124 124 124 124
Potato Starch 26 26 26 26 26
Sodium starch glycollate 24 - - - -
Sodium carboxy methyl cellulose - 24 - - -
Sodium lauryl sulphate - - 24 - -
Sodium chloride - - - 24  
Potassium chloride - - -   24
Purified Talc 30 30 30 30 30
Magnesium stearate 30 30 30 30 30
Polyvinyl pyrrolidone K-30 10% w/v in iso propyl alcohol
Total weight of core tablet 784 784 784 784 784
Coat Weight (% / Tablet)
GG:XG:Carragennan:Pectin
1:1:1:1 (4 % w/v) in 50:50 Ethanol:Water mixture
10 10 10 10 10
Table 2: Composition of various super disintegrating agents and osmotic agents used for core tablets of metronidazole (250 mg).
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