Compound Rapid Equilibrium Dialysis, % Bound  (Human Plasma) % CV* Rapid Equilibrium Dialysis % Bound  (Rat Plasma ) % CV*
Propranolol 79 1.3 78 2.3
Verapamil 90 0.5 90 1.3
Ketoconazole 99 1.0 99 1.5
Carbamazepine 80 1.0 83 2.1
Lidocaine 67 o.2 63 3.0
Erythromycin 79 0.1 84 1.5
Albendazole 80 1.0 90 4.0
Ranintidine 26 2.0 32 5.2
Ofloxacin 41 3.0 24 4.4
Atenolol 11 2.5 29 6.0
*Data represents n= replicates
Table 2: Comparison of Human and Rat Plasma Protein Binding Values for Set of Standard Compounds.
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