| Time (h) |
Marketed formulation |
Run 2a2 |
Run 16d4 |
Δ = Ref - Run 2a2 |
Δ = Ref - Run 16d4 |
R = Reference/ Run 2a2 |
R = Reference/ Run 16d4 |
| 1 |
17.6±0.21 |
27±0.007 |
21.2±0.08 |
9.4±0.03 |
3.6±0.14 |
0.651852±0.42 |
0.83±0.21 |
| 2 |
35.8±0.15 |
44.3±0.15 |
36.21±0.1 |
8.4±0.17 |
0.41±0.07 |
0.809955±0.28 |
0.98±0.14 |
| 3 |
51.6±0.21 |
57.8±0.17 |
52.13±0.12 |
6.4±0.009 |
0.53±0.28 |
0.809955±0.14 |
0.98±0.28 |
| 4 |
63.5±0.01 |
69.6±0.07 |
64.53±0.19 |
6.1±0.02 |
1.03±0.04 |
0.912356±0.05 |
0.98±0.02 |
| 5 |
74.4±0.28 |
78.6±0.06 |
75.32±0.28 |
4.2±0.01 |
0.92±0.7 |
0.946565±0.32 |
0.98±0.05 |
| 6 |
82.6±0.42 |
86.7±0.03 |
84.7±0.07 |
4.1±0.02 |
2.1±0.02 |
0.95271±0.06 |
0.97±0.04 |
| 7 |
91.0±0.17 |
92.4±0.51 |
94.47±0.12 |
1.4±0.35 |
3.47±0.17 |
0.984848±0.12 |
0.96±0.01 |
| 8 |
95.5±0.01 |
97.7±0.007 |
98.42±0.08 |
1.2±0.06 |
2.92±0.08 |
0.98759±0.10 |
0.97±0.007 |
| |
|
|
|
|
|
*t = 5.2006 |
*t = 4.281 |
*t indicates the significant difference at 5 level |
