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Figure 2: AFAe induced the expression of the IL-2 receptor CD25 (center panels) and the CD69 activation marker (right panels) on almost all CD3 CD56dim NK cells but not on the CD3- CD56bright NK cells. (Left panels) Isotype control plots. Contour plots show data from (top row) untreated (UT) cells and (bottom row) AFAe treated samples. The contour plots display data on CD3-CD56+ lymphocytes. The two dimensional plot allows evaluation of CD56 intensity versus expression of the activation marker CD69. The data shown are representative of three separate experiments using cells from three different donors. |