Gene GO category Fold change (+) Expression/ Function
Stra8 (Stimulated by Retinoic Acid gene 8) Reproduction ; germ cell development; spermatogenesis ; fertilization ; reproductive process ; cell differentiation 2.42 Role in premeiotic phase of germ cells, required for transition into meiosis [29]
Mea 1 (Male enhanced antigen 1) Reproduction; spermatogenesis; reproductive process; cell differentiation 5.46 Functions in late stages of spermiogenesis, expression in pachytene spermatocytes, cytoplasm of elongated spermatids [30]
Crem (cAMP responsive element modulator) Reproduction ; nucleus ; spermatogenesis ; gene expression ; regulation of gene expression ; reproductive process 3.69 Regulation of genes required for spermatid maturation [31]
Zfp42 (Zinc finger protein 42 or Reduced expression protein 1) Nucleus ; gene expression ; regulation of gene expression 8.31 Expression in spermatocytes [32]
Zfp35 (Zinc finger protein 35) Reproduction ; nucleus ; spermatogenesis ; gene expression ; regulation of gene expression ; reproductive process ; cell differentiation 4.44 Expression in pachytene spermatocytes [33]
Tnp1(Transition protein 1) reproduction ; nucleus ; spermatogenesis ; reproductive process ; cell differentiation 64.65 Expressed during spermiogenesis [34]
Mtl5 (metallothionein-like 5)/ Tesmin reproduction ; nucleus ; spermatogenesis ; reproductive process ; cell differentiation 105.95 Expressed in spermatocytes [35]
Prm1 (Protamine 1) reproduction ; nucleus ; germ cell development ; spermatogenesis ; reproductive process ; cell differentiation 2884 Expressed in spermatids [36]
Hils1(histone H1-like protein in spermatids 1 reproduction ; nucleus ; spermatogenesis ; gene expression ; regulation of gene expression ; reproductive process ; cell differentiation 2451 Spermatid-specificlinkerhistone.H1-likeproteinimplicatedinchromatin remodeling [37]
Table 5: Genes from different GOs: fold change up-regulation (+) of genes from microarray experiment and their reported expression or function in the context of spermatogenesis.
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