Trophic Factors Secreted from Stem Cells Major Functions
Adrenomedullin Cardioprotection
Angiogenin Angiogenesis
Angiopoetin-1 Angiogenesis
Bone morphogenetic protein Cell development
Endothelin Cardioprotection
Fibroblast growth factor Cell proliferation and migration
Hepatocyte growth factor Cardioprotection and angiogenesis
Insulin-like growth factor Cardioprotection
Interleukin-1 VEGF induction
Interleukin-6 VEGF induction
Macrophage migration inhibitory factor Immune-modulatory
Platelet-derived growth factor Cell proliferation
Thrombospondin-1 Cardiac remodeling prevention
Thymosin-b4 Cardioprotection
Transforming growth factor Cell proliferation and angiogenesis
Tumor necrosis factor-a Cell proliferation
Vascular endothelial growth factor Angiogenesis
Table 1: Lists of paracrine molecules secreted from MSCs [3]
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