Year Gender ASR for HCC/ 100,000 in Karachi 1995 - 1997 Males Females 5.7 3.7 1998 – 2002 Males Females 5.3 4.0 Year Gender ASR for HCC/ 100,000 in Larkana 2000 – 2002 Males Females 10.5 2.0 Year Gender ASR for HCC/ 100,000 in Hyderabad 1998 - 2002 Males Females 4.4 1.2 Year Gender ASR for HCC/ 100,000 in Quetta 1998 - 1999 Males Females 12.3 3.1 Gender   ASR for HCC/ 100,000 in Karachi 1995 - 1997 Males Females 5.7 3.7 1998 – 2002 Males Females 5.3 4.0 Year   ASR for HCC/ 100,000 in Larkana 2000 – 2002 Males Females 10.5 2.0 Year   ASR for HCC/ 100,000 in Hyderabad 1998 - 2002 Males Females 4.4 1.2 Year   ASR for HCC/ 100,000 in Quetta 1998 - 1999 Males Females 12.3 3.1

Table 2: Year wise increase in HCC cases with respect to gender in different cities of Pakistan. The male to female ratio is 3.6:1.0 [7,61]

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