Parameters Polar Location Outer membrane Inner membrane     Vrest = 0 Vrest = -78 mν Vrest = 0 Vrest = -78 mν Pore Density (N) 0 3.22*1010 3.22*1010 7.43*109 7.43*109 50° 7.5*1010 7.5*1010 1.54*1010 1.54*1010 100° 10.2*1011 8.7*1011 1.9*1011 1.64*1011 150° 4.25*1010 4.25*1010 9.28*109 9.28*109 200° 4.25*1010 4.25*1010 8.16*109 8.16*109 250° 2.64*1011 1.07*1011 5.04*1010 5.04*1010 300° 3.32*1010 3.32*1010 2.44*1010 2.12*1010 350° 7.5*1010 7.5*1010 9.6*109 7.6*109 Pore Radius (r) ( 0 1.17 1.11 1.09 1.05 50° 1.4 1.3 1.3 1.26 100° 2.36 2.29 2.2 2.13 150° 1.24 1.2 1.15 1.22 200° 1.2 1.16 1.11 1.08 250° 1.8 1.7 1.67 1.62 300° 1.54 1.5 1.44 1.39 350° 1.18 1.14 1.09 1.06

Table 1: Effect of restpotential on pore density and pore radius for intraorganelle nanoporation.

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