Genotypes

Clinicopathological Parameters

P

OR(%95CI)

rs3024994(C/T)

 

 

Gender

 

0.007

 

 

 

 

Female

Male

 

 

CC

 

 

52

225

 

1.00

CT

 

 

12

18

0.009

0.35(0.16-0.76)

rs3025021(C/T)

 

 

Tumor size

 

0.025

 

 

 

 

<5cm

≥5cm

 

 

CC

 

 

100

106

 

1.00

CT

 

 

18

33

0.091

1.73(0.92-3.27)

TT

 

 

8

2

0.072

0.24(0.05-1.14)

rs3025030(G/C)

 

 

Tobacco smoking

 

0.001

 

 

 

 

No or occasionally

Yes

 

 

GG

 

 

106

85

 

1.00

CG

 

 

30

59

0.001

2.45(1.45-4.14)

CC

 

 

4

9

0.095

2.81(0.84-9.43)

 

 

 

Alcohol drinking

 

0.013

 

 

 

 

No or occasionally

Yes

 

 

GG

 

 

113

78

 

1.00

CG

 

 

37

52

0.006

2.04(1.22-3.39)

CC

 

 

5

8

0.153

2.32(0.73-3.35)

 

 

 

Tumor location

 

0.023

 

 

Cardia

Corpus

Whole Stomach

Antrum

 

 

GG

90

31

10

39

 

 

CG

36

20

0

27

 

 

CC

3

5

0

4

 

 

rs3025039(C/T)

 

 

Tobacco smoking

 

0.042

 

 

 

 

No or occasionally

Yes

 

 

CC

 

 

108

89

 

1.00

CT

 

 

32

48

0.026

1.82(1.07-3.09)

TT

 

 

4

8

0.159

2.43(0.71-8.33)

rs833052(C/A)

 

 

VEGF expression

 

0.062

 

 

 

 

Negative

Positive

 

 

CC

 

 

31

73

 

1.00

AC

 

 

47

65

0.064

0.59(0.33-1.03)

AA

 

 

11

10

0.050

0.39(0.15-1.00)


P, Two-sided χ2 test

Table 3: Significant correlations with clinicopathological parameters and VEGF polymorphisms.