Figure 1: Tissue Engineering Principles: Cells are isolated from human or animal sources and expanded on two-dimensional cultures. Next, cells are embedded in an extracellular matrix analogue (scaffold), which facilitates proper cellular organization. This engineered tissue is implanted in the patient with the aim to promote regeneration of damaged tissue. Alternatively, it can be used in vitro to study human physiology and pathophysiology more accurately than with two-dimensional cultures.
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