SNPs Observed genotype frequency (%) ± 95% Confidence Interval (CI) Predicted genotype frequency (%) by Hardy-Weinberg Law ± 95% Confidence Interval (CI)
CYP3A4*1B
    CYP3A4*1A/ *1A
95.65 ± 2.82 95.70 ± 2.80
    CYP3A4*1A/ *1B
4.35 ± 2.82 4.25 ± 2.79
    CYP3A4*1B/ *1B
0 0.05 ± 0.30
n 115
Table 5: Genotype frequency according to Hardy-Weinberg equilibrium in opiatedependent patients.