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| Figure 3: DAVID functional clustering of 23 upregulated genes predicted to be the targets of miR-130a. 23 upregulated genes (also the putative targets of miR-130a) were uploaded into the DAVID server to highlight those genes that were highly enriched by functionally related GO terms. 11 of the 23 upregulated genes were associated with specific GO terms. Each column indicates a particular GO term, and each row indicates a particular gene. Colors in the 2-D map indicate whether a gene is reported in a corresponding GO term (green) or not (dark). ITPR2, inositol 1,4,5-triphosphate receptor, type 2; ATP1A2, ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide; SLC39A12, solute carrier family 39 (zinc transporter), member 12; ATP1B2, ATPase, Na+/ K+ transporting, beta 2 polypeptide; SLC1A2, solute carrier family 1 (glial high affinity glutamate transporter), member 2; CPT2, arnitine palmitoyltransferase 2; PCDHB5, protocadherin beta 5; ZFYVE21, zinc finger, FYVE domain containing 21; RAB34, member RAS oncogene family; FAM65B, family with sequence similarity 65, member B; BBS2, Bardet-Biedl syndrome 2. |
