| Genes |
Expression (controls)a |
Expression (AUD cases)a |
Effect sizeb |
Pnominalc |
Ppermutationd |
| FBXO21 |
9.47 |
9.59 |
0.12 |
0.001 |
0.002 |
| ITPR2e |
6.72 |
6.82 |
0.12 |
0.002 |
0.002 |
| FAM65B |
7.21 |
7.37 |
0.15 |
0.005 |
0.004 |
| ZFYVE21 |
10.06 |
10.26 |
0.23 |
0.006 |
0.006 |
| BBS2 |
9.17 |
9.31 |
0.18 |
0.005 |
0.007 |
| GPR177 |
7.78 |
7.99 |
0.23 |
0.007 |
0.008 |
| JARID2e |
8.27 |
8.41 |
0.17 |
0.011 |
0.010 |
| RAB34 |
7.05 |
7.34 |
0.29 |
0.012 |
0.011 |
| C10orf54e |
6.89 |
7.25 |
0.31 |
0.012 |
0.012 |
| SPON1 |
8.02 |
8.43 |
0.43 |
0.034 |
0.022 |
| ATP1A2 |
9.85 |
10.17 |
0.44 |
0.027 |
0.024 |
| ATP1B2 |
9.41 |
9.83 |
0.44 |
0.056 |
0.029 |
| WIF1 |
7.18 |
7.44 |
0.39 |
0.037 |
0.032 |
| AFF4 |
7.66 |
7.80 |
0.17 |
0.022 |
0.033 |
| BAG3e |
7.74 |
8.25 |
0.45 |
0.035 |
0.033 |
| TUBB2Be |
12.31 |
12.66 |
0.32 |
0.029 |
0.033 |
| SDC4 |
8.01 |
8.53 |
0.49 |
0.040 |
0.034 |
| CPT2 |
7.43 |
7.59 |
0.15 |
0.029 |
0.035 |
| SLC39A12 |
7.25 |
7.54 |
0.35 |
0.060 |
0.038 |
| PCDHB5 |
6.65 |
6.69 |
0.05 |
0.073 |
0.040 |
| SLC1A2 |
10.29 |
10.74 |
0.54 |
0.040 |
0.041 |
| GJA1 |
8.78 |
9.23 |
0.54 |
0.054 |
0.047 |
| TMEM192 |
6.71 |
6.75 |
0.04 |
0.050 |
0.048 |
aMean gene expression levels in controls (or AUD cases) measured by Illumina's
HT-12 v4 Gene Expression BeadChip.
bEffect size (or regression coefficients) obtained by multiple linear regression
analysis with adjustment for sex, age, and PMI.
cObserved P values obtained by multiple linear regression analysis with adjustment
for sex, age, and PMI.
dPermutation P values obtained by R package lmPerm analysis.
eGenes with expression levels negatively correlated with that of miR-130a. |
