Predictor OR 95% CI P
DSM IV alcohol dependence symptoms 0.87 (0.86a) 0.78-0.99 (0.73-1.02a) 0.04* (0.08a)
Craving measured by OCDS 0.94 (0.92a) 0.90-0.98 (0.86-0.98a) <0.01** (<0.01**a)
OCDS “resistance/controlĀ  impairment 0.87 (0.84) 0.81-0.94 (0.76-0.92) <0.001*** (<0.001***)
OCDS “obsession” 0.92 (0.90) 0.85-1.00 (0.80-1.01) 0.04* (0.06)
OCDS “interference” 0.95 (1.00a) 0.85-1.05 (0.86-1.16a) 0.31 (0.98)
Craving measured by VAS 0.86 (0.83a) 0.79-0.94 (0.74-0.92a) <0.001*** (<0.01**a)
Symptoms of depression measured by BDI 0.96 (0.96a) 0.92-1.01 (0.90-1.03a) 0.08 (0.23a)
Dependent variable was categorized as 1=good adherence with naltrexone and 0=poor adherence)
A=Adjusted for Socio-Demographic Variables Age, gender, marital status, employment and education
Table 3: Predictors of patients' (n=299) adherence to naltrexone medication in a treatment for problem drinking:alcohol dependence symptoms, alcohol craving and symptoms of depression at treatment entry