Figure 3: Effect of NT69L on alcohol withdrawal signs
Male Wistar rats were exposed to alcohol (14 h on/10 h off) or air for 3 weeks. Alcohol exposure was discontinued and 2 h later the rats were injected with either NT69L or saline i.p. The following withdrawal tests were conducted: (a) Locomotor activity; (b) Sensitivity to a nociceptive stimulus; (c) muscle rigidity; (d) body temperature as explained in detail in the text. * Significantly different from all other treatment (P<0.05). (n) Number of animals in each group. A=alcohol, NT=NT69L.