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| Figure 4: Effect of PMMA on monoamine levels in the mouse limbic forebrain. Mice were sacrificed 30 min after PMMA (5 and 30 mg/kg, i.p.) injection. The concentrations of the monoamines [dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), 3-methoxytyramine (3MT), serotonin (5-HT) and 5-hydroxyindoleacetic acid (5HIAA)] were analyzed using an HPLC system. Each column represents the mean with the S.E.M. of 6 animals. *P<0.05, **P<0.01 vs. saline (SAL)-treated group. #P<0.05 vs. PMMA (5 mg/ kg)-treated group. |
