Figure 1: Graph represents average ethanol intake (g/kg/day) during the 10 days of re-exposure to ethanol. Based on GLM repeated measures followed by one-way ANOVA, ceftriaxone treatment (200 mg/kg/day) resulted in a significant reduction in ethanol consumption compared to saline vehicle-treated control group from Day 2 to Day 9. Lower dose of ceftriaxone (50 mg/kg/ day) did not cause any reduction in ethanol intake by P rats. Data are expressed as mean ± SEM (*: p<0.05). Saline group (n=5); ceftriaxone groups (50 and 100 mg/kg, i.p. body weight, n=6 for each group)