Remaining predictors B SE Beta t P
Physicala          
(constant) 117.867 9.006   13.087 <0.001**
Age -0.584 0.241 -0.175 -2.428 0.017*
Employment status          
Unemployed -19.818 4.47 -0.505 -4.434 <0.001**
Employed (low paid) -9.148 3.84 -0.253 -2.383 0.019*
Employed (high paid)   0 [Reference]     NA
Injection bebaviour          
Frequent injection bebaviour -6.666 2.45 -0.184 -2.721 0.008**
No injection behaviour   0 [Reference]     NA
Global Severity Index -10.895 2.143 -0.383 -5.083 <0.001**
Psychologicalb          
(constant) 96.624 5.587   16.579 <0.001**
Employment status          
Unemployed -17.792 4.292 -0.427 -4.145 <0.001**
Employed (low paid) -8.733 3.79 -0.227 -2.304 0.023*
Employed (high paid)   0 [Reference]     NA
Marital status          
Unmarried -0.787 3.164 -0.018 -0.249 0.804
Married 8.588 2.735 0.228 3.14 0.002**
Divorced/widowed   0 [Reference]     NA
Educational level          
Elementary school -9.84 3.674 -0.261 -2.678 0.009**
High school -8.888 3.617 -0.232 -2.457 0.016*
Superior to special course   0 [Reference]     NA
Injection bebaviour          
Frequent injection bebaviour -4.945 2.302 -0.129 -2.148 0.034*
No injection behaviour   0 [Reference]     NA
Global Severity Index -14.258 2.023 -0.472 -7.049 <0.001**
Socialc          
(constant) 89.508 6.028   14.85 <0.001**
Employment status          
Unemployed -15.405 4.836 -0.362 -3.186 0.002**
Employed (low paid) -8.511 4.256 -0.217 -0.2 0.048*
Employed (high paid)   0 [Reference]     NA
Marital status          
Unmarried 2.833 3.686 0.062 0.769 0.444
Married 10.688 3.178 0.278 3.363 0.001**
Divorced/widowed   0 [Reference]     NA
Global Severity Index -15.951 2.303 -0.517 -6.925 <0.001**
Environmentald          
(constant) 80.16 4.958   16.168 <0.001**
Employment status          
Unemployed -8.927 3.957 -0.254 -2.256 0.026*
Employed (low paid) -4.081 3.48 -0.126 -1.173 0.244
Employed (high paid)   0 [Reference]     NA
Marital status          
Unmarried 3.675 3.01 0.097 1.221 0.225
Married 10.838 2.604 0.341 4.162 <0.001**
Divorced/widowed   0 [Reference]     NA
Injection bebaviour          
Frequent injection bebaviour -6.817 2.177 -0.21 -3.132 0.002**
No injection behaviour   0 [Reference]     NA
Global Severity Index -12.26 1.896 -0.481 -6.465 <0.001**
#The analysis only includespatients who have undergone Nucleus accumbens ablative surgery.
**Correlation is significant at the 0.01level (2-tailed);*Correlation is significant at the 0.05level (2-tailed). Frequent injection behavior: at least 2 times of injection behavior per day.
aR2=0.560,adjusted R2=0.538,P<0.001**; bR2=0.673,adjusted R2=0.646,P<0.001**; cR2=0.560,adjusted R2=0.538,P<0.001**; d R2=0.574,adjusted R2=0.548,P<0.001**.
Table 5: Final model of the linearmultivariate regression analysis including significant predictors of different WHOQOL-BFEF subscores#