1.Antibiotics (penicillin G potasium, 50 mg tb 4 x1, 4 days)

2.Corticosteroids (Prednisolone or prednison equivalents 10-30 mg / day 1-2 months)

3. Colchicine 0,5-2 mg/ day, 7-14 days

4.Dapsone 25-100 mg / day, 3 days

5.Clofazimin 100 mg/ day, 6 months

6.Pentoxifylline 300-400 mg 1-3x1,1 month

7.Zinc sulphate, vitamin B12, iron, folic acid replacement

8.Immunomodulators: Thalidomide 50-100 mg / day, levamisole 150 mg 3 times a week, 6 months

9.Homeopathic materials (mercurius solubilis, Natrum muriaticum, phosphorus, sulphuric acid, nitric acid)

Table 3. Systemic Pharmaceutical Treatment