Temazepam 0 mg (Placebo)

Temazapam 30 mg

p^

Test

Index

Baseline

Post—tx

Baseline

Post—tx

 

 

 

 

 

 

 

 

SRT2-SRT1
  -Psychomotor Fatigue

Reaction Time (ms)

-1.86±43.13

8.14±25.48

24.89±37.52

10.78±29.71

0.85

 

 

 

 

 

 

 

CRT
  -Attention/
   Working Memory

Reaction time (ms)

886.43±55.66

888.11± 38.36

890.61±86.54

865.00±64.45

0.42

Correct (%)

89.46±8.46

94.59±5.79

85.63±19.92

94.96±4.24

0.89

 

 

 

 

 

 

 

1–Back
  -Working Memory

Reaction time (ms)

795.21±77.31

837.64±61.46

871.11±156.21

853.17±82.23

0.68

Correct (%)

93.56±8.15

94.9±5.67

92.60 ±6.97

95.60±5.13

0.80

2–Back
  -Working Memory

Reaction time (ms)

920.36±69.33

960.43±189.42

1052.83±202.44

923.72±176.79

0.70

Correct (%)

74.86±10.27

77.1±8.26

72.73±15.92

72.33±18.61

0.54

 

 

 

 

 

 

 

HVLT-R
  -Verbal Learning/
   Episodic Memory

Total words recalled (#)

21.14±7.52

21.86±5.24

21.33±4.92

21.11±3.86

0.75

Delayed Recall (%)

78.91±13.69

61.29±26.79

77.50±20.57

66.89±27.50

0.69

 

 

 

 

 

 

 

BVMT-R
  -Visuospacial Learning/
   Episodic Memory

Total objects recalled (%)

13.57±4.20

11.57±4.16

15.67±5.50

13.44±3.54

0.35

Delayed Recall (%)

87.14±20.58

94.0±21.26

91.78±37.67

94.11±20.65

0.99

 

 

 

 

 

 

 

Stroop Test
  -Selective Attention

Words Read (#)

84.86±18.88

88.57±14.68

86.89±15.19

88.11±13.59

0.95

Colors Read (#)

62.00±9.24

62.29±9.76

59.89±9.52

66.89±8.15

0.32

Color-Words Read (#)

36.43±11.66

38.57±10.28

35.89±7.39

39.89±7.64

0.77

Interference

1.00±10.13

2.00±8.33

0.56±7.20

1.67±5.20

0.92

 

 

 

 

 

 

 

COWAT
  -Verbal Fluency

Words Pronounced (#)

12.57±4.20

14.86±5.27

10.33±2.50

12.78±5.14

0.44

 

 

 

 

 

 

 

SST
  -Response Inhibition

RT – Go Trials (ms)

584.74±97.80

586.02±124.38

650.96±128.42

573.73±183.88

0.40

Baseline Accuracy (%)

98.90±1.20

98.53±1.50

93.95±8.47

95.40±5.13

0.24

SSRT (ms)

175.60±60.77

145.16±36.76

190.41±46.77

216.02±66.86

0.08

^ p values indicate differences between post-treatment groups

Table 2 : Baseline and post-treatment (post—tx) performance on neurocognitive functioning

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