Figure 4: Two-bottle choice ethanol intake in female ENT1 null vs. wild-type mice. Female ENT1 null mice (n=9) showed increases in both ethanol consumption (a) and ethanol preference (b), compared to female wild-types (n=10). Volumetric analysis indicated that ENT1 null mice drank significantly more ethanol than wild-types (c), but that water consumption was similar between genotypes (d). Body weight was significantly lower in ENT1 null vs. wild-type mice (e). Bars represent mean ± SEM. *P < 0.05 by two-tailed t-test.