Figure 1: Adherent cells derived from bone marrow cells of mouse and rat. Bone marrow cells collected from femurs and tibias of mouse (A-G) and rat (H-N) were cultured in the presence (D-F and K-M) or absence (A-C and H-J) of human M-CSF for 3 (A, D, H, and K), 7 (B, E, I, and L), and 14 (C, F, J, and M) days. Scale bars = 100 μm. The number of adherent cells derived from bone marrow cells from mice (G) and rats (N) was counted. ***p < 0.001 vs. cells cultured in the absence of M-CSF at each time points. A significant difference of the main effect of treatment × culture day interaction at P < 0.0001 vs. groups cultured in the absence of M-CSF in G and N. N; number of samples.