| |
BICOMBO |
STEAL |
| ABC/3TC |
TDF/FTC |
ABC/3TC |
TDF/FTC |
| |
n=167 |
n=166 |
n=178 |
n=179 |
| Lost to follow up (%) |
13 |
7.8 |
27 |
16.3 |
4 |
2.2 |
2 |
1.1 |
| Baseline ABC (%) |
12 |
7.2 |
18 |
10.8 |
36 |
20.2 |
37 |
20.7 |
| Baseline TDF (%) |
44 |
26.3 |
56 |
33.7 |
54 |
30.3 |
53 |
29.6 |
| Baseline PI (%) |
17 |
10.2 |
16 |
9.6 |
42 |
23.6 |
41 |
22.9 |
| NRTI exposure [years(sd)] |
4.4 |
2.9 |
4.1 |
2.9 |
5.7 |
3.4 |
5.9 |
3.8 |
| Male (%) |
130 |
77.8 |
127 |
76.5 |
176 |
98.9 |
173 |
96.6 |
| Male homosexual transmission (%)* |
55 |
35.0 |
51 |
32.1 |
157 |
88.2 |
159 |
88.8 |
| Prior AIDS (%) |
63 |
37.7 |
65 |
39.2 |
31 |
17.4 |
28 |
15.6 |
| Age [years(sd) |
43 |
9 |
45 |
10 |
46 |
9 |
44 |
8 |
| CD4 count [cells/mm3(sd)] |
533 |
292 |
554 |
299 |
627 |
306 |
599 |
257 |
| Creatinine clearance [ml/min(sd)] |
105 |
25.2 |
100 |
27 |
112 |
26.3 |
114 |
27.4 |
| eGFR [ml/min/1.73m2 (sd)] |
75.7 |
31.6 |
73.3 |
34 |
98.2 |
22.4 |
98.4 |
17 |
| Triglycerided[mmol/L(sd)] |
1.8 |
1.1 |
2 |
1.4 |
2.2 |
2.7 |
2.3 |
3 |
| Total:HDL ratio |
4 |
1.3 |
4.2 |
1.4 |
4.3 |
1.6 |
4.4 |
1.4 |
| Total cholesterol[mmol/L(sd)] |
5.2 |
1 |
5.4 |
1 |
5.2 |
1 |
5.4 |
1.3 |
| HDL cholesterol[mmol/L(sd)] |
1.4 |
0.4 |
1.4 |
0.5 |
1.3 |
0.4 |
1.3 |
0.4 |
| LDL cholesterol[mmol/L(sd)] |
3.1 |
0.8 |
3.1 |
0.9 |
3.1 |
0.9 |
3.1 |
0.9 |
| ALT > ULN** |
48 |
31.4 |
54 |
34.8 |
40 |
22.4 |
36 |
20.2 |
| AST >ULN† |
23 |
15.6 |
36 |
24.8 |
36 |
20.1 |
31 |
17.4 |
