HRQOL Questionnaire items HRQOL items scores [median (IQR)]
Adherence Drug side effects Self-medication
Yes (n=205) No (n=26) p No (n=183) Yes (n=48) p No (n=97) Yes (n=134) p
Global HRQOL score 80.98
(73.76-87.22)
75.44
(70.11-81.89)
0.01 81.27
(73.76-87.36)
78.23
(72.04-82.62)
0.03 81.11
(74.42-87.97)
80.12
(71.64-85.91)
0.08
GHP 60 (50-70) 55 (45-65) 0.04 60
(50-70)
60
(50-70)
0.69 60
(50-70)
60
(50-70)
0.88
PF 100
(91.66-100)
91.66
(66.66-100)
0.05

100

(91.66-100)

91.66
(83.33-100)
0.01 100 (91.66-100) 100
(91.66-100)
0.07
RF 100
(100-100)
100
(100-100)
0.68 100
(100-100)
100
(100-100)
0.55 100
(100-100)
100 (100-100) 0.31
P 77.77
(55.55-100)
66.66
 (44.44-100)
0.14

88.88
(55.55-100)

66.66
(55.55-100)
0.24 100
(55.55-100)
66.66
(55.55-100)
0.10
SF 100
(100-100)
100
(100-100)
0.26 100
(100-100)
100
(100-100)
0.44 100 (100-100) 100
(100-100)
0.34
MH 68
(56-80)
68
(52-76)
0.77 68
(56-80)
64
(52-78)
0.20 72
(56-80)
68
(56-76)
0.04
EF 85
(70-90)
80
(65-90)
0.32 85
(70-95)
77.50
(62.5-90)
0.05

85

(70-95)

80
(70-90)
0.03
HD 95
(80-100)
92.5
(65-100)
0.38 95
(80-100)

92.5

(72.5-100)

0.49

100

(80-100)

95
(75-100)
0.13
CF 90
(80-100)
85
(75-100)
0.22 95
(80-100)
87.5
(70-100)
0.03 95
(85-100)

85

(75-100)

0.007
QL 75
(50-100)
50
(50-75)
0.04 75
(50-100)
75
(50-100)
0.34 75
(50-100)
75
(50-100)
0.43
HT 75
(50-75)
50
(50-75)
0.15 75
(50-75)
75
(50-75)
0.96 75
(50-75)
75
(50-75)
0.76
p: Mann-Whitney test, IQR: interquartile range; GHP: General Health Perceptions, PF: Physical Functioning, RF: Role Functioning, P: Pain, SF: Social Functioning, MH: Mental Health, EF: Energy/Fatigue, HD: Health Distress, CF: Cognitive Functioning, QL: Quality of Life, HT: Health Transition.
Table 2: HRQOL scores related to adherence, drug side effects and self-medication.