| Factors predicting good outcome |
Factors present in our patient |
| At diagnosis |
|
| Non-progressive".Neurological symptoms [5] |
No |
| CD4+ T-cell count >100 cells/mmł |
No |
| Gadolinium Contrast enhancement on MRI [5] |
Yes |
| Early Interventions and response |
|
| Earlier use of steroids after the recognition of IRIS [5] |
Yes |
| Radiological improvement within 6 month after introduction of HAART [17] |
Yes |
| Factors predicting poor outcome |
|
| Progressive Neurological symptoms [5] |
Yes |
| Worsening of preexisting PML [5] |
Yes |
| Late use of steroids in the course of IRIS [5] |
No |
| Lesion load on PML-IRIS MRI >2 [5] |
Our patient had diffused multiple lesions (Lesion load 51) on MRI including cerebellar white matter, right thalamus, left parietal lobe. right putamen, right subinsular region, right posterior frontal lobe and bilateral periventricular white matter. Post treatment lesion load decreased to 25. |
