Parameters HIV-1 infected children Matched healthy controls p values
VC (L) 3.37 ± 0.72 (2.19-4.93) 3.69 ± 1.1 (2.51-6.58) 0.44
FEV1 (L) 2.90 ± 0.64 (2.05-4.59) 3.25 ± 1.0 (2.21-5.53) 0.34
FEF25-75 (L/s) 3.46 ± 0.96 (2.27-6.16) 4.08 ± 1.4 (2.55-7.40) 0.21
FEV1 / FVC (%) 88 ± 6% (77-98) 90 ± 5% (82-98) 0.43
TLCO  (ml/mn/Hg mm) 24.18 ± 9.3 (15.7-57.5) NA NA
Parameters (ppv) HIV-1 infected children Matched healthy controls  
VC 101.4 ± 14.7% 103.5 ± 15.5% 0.98
FEV-1 92.6 ± 12.5% 100.2 ± 13.9% 0.052
FEF25-75 98.1 ± 21.2% 112.1 ± 24.6% 0.14
FEV1 / FVC 91.9 ± 7.7% 97.1 ± 6% <0.0001
TLCO 102.9 ± 23.8% NA  
mean ± standard deviation and range for spirometric values. HIV-1 vertically infected children (n: 17) and healthy matched control (n: 17). Units: (L) liter, (L/s) liter per second, (ml/min/Hg mm) milliliter per minute per Hg millimeter. NA: non available, ppv: percentage of predicted value. Mean ± standard deviation for
spirometric values expressed as percentages of predicted values according to the anthropometric data of each patient.
p values: Mann-Whitney comparison
Table 2