| |
Lipohypertrophy |
Lipoatrophy |
Lipodystrophy |
| Model 1* |
Model 1† |
Model 1* |
| Gender |
|
|
|
| Male |
1.00 |
1.00 |
1.00 |
| Female |
1.09 (0.85–1.40) |
0.97 (0.79–1.21) |
0.92 (0.80–1.06) |
| P value |
0.5 |
0.8 |
0.3 |
| Age (years) |
1.00 (0.99–1.01) |
0.99 (0.98–0.99) |
1.00 (0.99–1.00 ) |
| P value |
0.8 |
0.035 |
0.2 |
| Skin color |
|
|
|
| Caucasian |
1.00 |
1.00 |
1.00 |
| Non-Caucasian |
1.31 (1.02–1.68) |
1.09 (0.88–1.35) |
1.12 (0.97–1.29) |
| P value |
0.03 |
0.4 |
0.13 |
| Education (years) |
1.02 (0.99–1.05) |
0.95 (0.93–0.98) |
0.99 (0.97–1.01) |
| P value |
0.18 |
0.001 |
0.19 |
| |
Model 2* |
Model 2†† |
Model 2† |
| Smoking (pack-years) |
|
|
|
| 0 |
1.00 |
1.00 |
1.00 |
| 1-19 |
0.86 (0.67–1.17) |
1.16 (0.89–1.52) |
1.27 (1.07–1.52) |
| ≥20 |
0.99 (0.71–1.39) |
1.75 (1.31–2.35) |
1.06 (0.89–1.26) |
| P value |
0.6 |
<0.001 |
0.016 |
| Physical activity (min/week) |
|
|
|
| ≥150 |
1.00 |
1.00 |
1.00 |
| <150 |
1.06 (0.83–1.36) |
0.80 (0.64–1.00) |
0.94 (0.81–1.08) |
| P value |
0.6 |
0.046 |
0.4 |
| |
Model 3** |
Model 3††† |
Model 3† |
| Body mass index (kg/m2) |
1.09 (1.07–1.11) |
0.94 (0.91 – 0.97) |
1.00 (0.99 – 1.02) |
| P value |
<0.001 |
< 0.001 |
0.6 |
| CD4 (cells/mm3) |
|
|
|
| ≥350 |
1.00 |
1.00 |
1.00 |
| 200-349 |
0.71 (0.49–1.03) |
0.85 (0.63–1.16) |
0.90 (0.74–1.09) |
| <200 |
0.58 (0.30–1.11) |
1.16 (0.85–1.59) |
0.98 (0.77–1.26) |
| P value |
0.07 |
0.3 |
0.5 |
| Viral load (copies/mL) |
|
|
|
| <50 |
1.00 |
1.00 |
1.00 |
| ≥50 |
0.98 (0.57–1.70) |
0.88 (0.54–1.42) |
1.16 (0.77–1.73) |
| P value |
1.0 |
0.6 |
0.5 |
| Time since diagnosis of HIV infection (years) |
|
|
|
| <3 |
1.00 |
1.00 |
1.00 |
| 3-5 |
1.12 (0.87–1.45) |
0.86 (0.65–1.15) |
1.06 (0.90–1.26) |
| ≥6 |
1.25 (0.88–1.77) |
0.96 (0.72–1.29) |
1.11 (0.92–1.34) |
| P value |
0.4 |
0.6 |
0.5 |
*Adjusted for skin color and education
**Adjusted for skin color, education, BMI, and CD4
† Adjusted for age and education
††Adjusted for age and education, physical activity, and smoking
†††Adjusted for age and education, physical activity, smoking, and BMI
†Adjusted for skin color, education, and smoking |
|
