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| Figure 1: Exhaled H2O2 as marker of oxidative stress in HIV-infected patients without signs and symptoms of opportunistic lung disease (OLD-negative) and with signs and symptoms of concomitant respiratory tract infection without definite diagnosis of OLD (RTI-positive). (A - top) Dot plot of individual results in healthy controls and HIV-1 infected patients. Box plot shows the geometric mean as a solid line and 95% confidence intervals as a rectangle. (B - bottom) Fold increase of geometric mean exhaled H2O2, resting and fMLP-induced peak whole blood chemiluminescence (CL) in OLD-negative patients against healthy controls. Raw data vs. adjusted for differences in polymorphonuclear leukocytes count (PMNs) among groups with ANCOVA (not applicable for exhaled H2O2 - assumptions not met). |
