Bivariate analysis Multivariate analysis, n =793
  Occurrence Cox   Fine-Gray   Cox   Fine-Gray  
Characteristics n =1136 % HR$crude[80% CI] P SHRcrude[80% CI] P HRajusted[95% CI] P * SHRajusted[95% CI] P *

Age at Ti **(year)

0.0048

0.0013

0.0264

0.0058

[18 – 50]

210

21.81

1(Reference)

 

1(Reference)

 

1(Reference)

 

1(Reference)

 

[50 – 82]

  55

31.79

1.53 [1.26–1.86]

 

1.61 [1.33–1.95]

 

1.47 [1.04–2.07]

 

1.60 [1.14–2.25]

 

Therapeutic education

<0.0001

<0.0001

0.0241

0.0341

No

202

22.20

1(Reference)

 

1(Reference)

 

1(Reference)

 

1(Reference)

 

Yes

  63

27.88

1.77 [1.47–2.14]

 

1.57 [1.30–1.90]

 

1.43 [1.04–1.97]

 

1.39 [1.02–1.89]

 

AIDS-defining illness

N=1092

100%

0.0006

0.0129

0.0511

0.1605

No

209

22.21

1(Reference)

 

1(Reference)

 

1(Reference)

 

1(Reference)

 

Yes

  47

31.13

1.74 [1.41–2.14]

 

1.50 [1.21–1.86]

 

1.45 [0.99–2.10]

 

1.31 [0.89–1.92]

 

VL (log10 copie/mm3) Ti **

N=829

100%

0.0216

0.0173

0.0392

0.0308

[1.7– 4.0]

  32

16.75

1(Reference)

1(Reference)

1(Reference)

1(Reference)

 

[4.0– 5.0]

  86

26.71

1.74 [1.33–2.27]

1.75 [1.35–2.28]

1.71 [1.12–2.60]

1.73 [1.15–2.60]

 

≥ 5.0

  79

25.00

1.66 [1.26–2.17]

1.66 [1.27–2.17]

1.41 [0.91–2.18]

1.48 [0.97–2.26]

 
* P-value obtained by backward stepwise regression
** Ti : Time of HAART initiation
$ Hazard Ratio obtained by Cox model
Subdistribution Hazards Ratio obtained by Fine-Gray model
Table 2: Baseline risk factors of first line HAART discontinuation for intolerance: Cox and Fine-Gray models.