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Figure 3: C. albicans percent killing by Hst-5 (5μg/ml) and pooled saliva in the absence (S) and presence (S+Ab) of the Hst-5 antibody. Drastic decrease in saliva’s initial anti-candidal potency in the presence of the antibody indicating loss of activity due to Hst-5 neutralization. Error bars indicate the standard errors of the means. All experiments were performed in triplicate on more than one occasion. *** P<0.001 (Hst-5 compared to PBS); * P<0.05 (S compared to PBS; S+Ab compared to S). |