Patient groups HC PTB HIV-1 subtype C HIV-PTB Patient subgroups     Total HIV Above 500 cells/μl 500>X>250 cells/μl Below 250 cells/μl   Subjects 20 12 27 8 10 9 8 Age [Median years] 28.5 34 32 27 30 37 30 %Males 60 100 59.3 62.5 60 55.6 75 %Females 40   40.7 37.5 40 44.4 25 WBC count 7300 10900 6300 6800 6250 5800 6800 T-cell count [CD3+] 1401 970.5 1738 2403 1811 1475 1095 Th cells count [CD3+CD4+] 849 459.5 345.0 706 348 172 171 Lymphocytes [CD45+] 1954 1579 2377 3477 2424 1587 1888 Hb g/dl 13.8 12.5 13.30 14.2 14.45 10.2 10 HC: Healthy control; PTB: pulmonary Mycobacterium tuberculosis; Above 500 cells/μl: HIV-1 subjects with CD4 count above 500 cells/μl; 500>X>250 cells/μl: HIV-1 subjects with CD4 count between 500 and 250 cells/μl; Below 250 cells/μl: HIV-1 subjects with CD4 count less than 250 cells/μl.

Table 1: Demographic and immunological characteristic of individuals within studied subgroups. Data expressed as median.There was no significant difference between CD4 count from HIV-1 subjects with CD4 count >250 cells/μl and HIV-1/PTB co-infected individuals. Strangely, we found significantly low mean CD4 count in individuals with active PTB [HIV-1/2 negative] when compared to HC.

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