Variable Control  (n=202) Cases (n=78) Univariate Odds Ratio (95%CI) P value
Age(years ± SD)
[Range]
Mean 35.35 ± 7.58 38.10 ± 7.89 0.95 (0.92,0.98) 0.008
  [20-62] [24-63]  
Sex Male 146 (72.3%) 66 (84.6%) 2.11(1.06,4.19) 0.031
Female 56 (27.7%) 12 (15.4%)  
Baseline CD4 count ± SD Mean 206.93 ± 169.91 103.92 ± 87.27 1.06(1.01,1.09) <0.0001
Patients who had TB(%) 0 times 135 (66.83%) 32 (41.1%) 0.36(0.23,0.56) <0.0001
1 times 62 (30.69%) 34(43.6%)  
2 times 05 (2.45%) 12 (15.4%)  
Taken private treatment(%) Yes 93 (46%) 37 (47.4%)   0.798
No 109 (54%) 41 (52.6%)  
Last NRTI  regimen Stavudine 131(64.9%) 47 (60.2%)   0.315
Zidovudine 71 (35.1%) 31 (39.7%)  
Negative change in weight in    last 24 months* Yes 66 (32.7%) 57 (73.1%) 1.36(3.5,11.63) <0.0001
No 136 (67.3%) 18 (23.1%)  
Peak CD4 count during first line treatment ± SD(Range) Mean 676.70 ± 276.20 236.19 ± 165.88 1.001(1.00,1.01) <0.0001
  (57-1809) (12-977)  
Time duration for peak CD4 count ± SD(Range) Mean 45.02 ± 12.60 21.89 ± 21.55 1.14(1.10,1.17) <0.0001
  (12-72) (05-156)  
* 3 patients on second line had no weight change available. SD= Standard deviation
Table 1: Baseline characteristic of the patients.