Characteristics AHR [95%CI] p-value
Marital status
Married
Single
Divorced
Widowed
1
1.25 (0.83-1.87)
0.57 (0.38-0.84)
2.18 (1.30-3.64)
0.287
0.005*
0.003*
Educational status
Not educated
Primary
Secondary
Tertiary
1
1.34 (0.90-1.99)
1.09 (0.66-1.79)
1.05 (0.49-2.21)
0.151
0.747
0.898
Occupational status
Farmer
Merchant
Employed
Daily laborer
House wife
Unemployed
Student
1
0.30 (0.17-0.53)
0.22 (0.12-0.40)
0.79 (0.47-1.35)
0.55 (0.29-1.03)
0.59 (0.35-1.03)
0.15 (0.06-0.38)
<0.0001*
<0.0001*
0.388
0.058
0.063
<0.000*
Follow up body mass index (kg/m2)
<=18.4
18.5-22.9
>=23
1
1.05 (0.74-1.48)
0.82 (0.51-1.31)
0.805
0.400
ART
No
Yes
1
0.52 (0.35-0.78)
<0.002*
Follow up ART regimens ¥
D4T+3TC+NVP
D4T+3TC+EFV
AZT+3TC+NVP
AZT+3TC+EFV
TDF+3TC+EFV
TDF+3TC+NVP  
1
0.45 (0.15-1.36)
0.64 (0.32-1.29)
1.14 (0.27-4.82)
0.47 (0.22-1.01)
1.33 (0.21-8.55)
0.157
0.211
0.861
0.053
0.763
  Base line Follow up
 AHR [95%CI] p- value AHR [95%CI] p-value
CD4 count (cells/μl )
<=100
101-199
200-350
351-499
>=500
1
0.46 (0.19-1.13)
0.59 (0.26-1.31)
0.60 (0.26-1.43)
0.52( 0.22-0.25)
0.089
0.191
0.251
0.142
1
0.56 (0.24-1.31)
0.68 (0.31-1.49)
0.39 (0.17-0.87)
0.32 (0.14-0.73)
0.182
0.338
0.022*
0.007*
Functional status
Working
Ambulatory
Bed ridden
1
1.99 (0.67-1.47)
0.98 (0.36-2.65)
0.961
0.965
1
1.12 (0.67-1.86)
1.49 (0.57-3.93)
0.664
0.414
Prophylaxis exposure
No
Yes
1
0.55 (0.33-0.91)
0.021* 0.49 (0.28-0.87) 0.014*
Prophylaxis Adherence
Good
Fair
Poor
1
0.92 (0.16-5.41)
2.96 (0.31-28.14)
0.925
0.346
1
7.27 (1.31-40.45)
3.59 (0.52-22.69)
0.023*
0.194
ART adherence
Good
Fair
Poor
1
14.83 (1.86-12.41)
6.64 (0.31-144.60)
0.011*
0.229
1
1.91 (0.38-9.67)
1.81 (0.09-36.34)
0.435
0.697
*significant at α=5%
AHR=adjusted hazard rate
¥ d4T: Stavudine; 3TC: Lamivudine; NVP: Nevirapine; EFV: Efavirenz; AZT:
Zidouvudine; TDF: Tenofovir disoproxil fumarate
Table 4: Multivariate cox proportional hazard model of the association between base line and follow up characteristics and any OI recurrence in study participants’ in Debre
Markos Hospital and Health Center, Northwest Ethiopia, between 25th March 2007 and 24th March, 2013.
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