| Variable |
Incidence rate
(/100 person-years) |
Hazard ratio* (95% CI) |
p |
| Age |
|
|
|
| ≤30 |
14 |
1.62(1.25-2.10) |
0.000 |
| 30-40 |
8.6 |
1.40(1.10-1.72) |
0.000 |
| >40 |
4.7 |
1 |
|
| Gender |
|
|
|
| Female |
7 |
1 |
|
| Male |
8 |
1.05(0.89-1.30) |
0.60 |
| HIV diagnosis period |
|
|
|
| 2005-2008 |
2.5 |
1 |
|
| 1997-2004 |
7 |
1.15(0.92-1.42) |
0.20 |
| 1988-1996 |
14 |
1.64(1.31-2.10) |
0.000 |
| CD4 cell count |
|
|
|
| Initial CD4 < 200/mm3 |
2.8 |
0.80(0.60-1.10) |
0.082 |
| Initial CD4 < 200-499/mm3 |
7 |
1.10(0.92-11.30) |
0.30 |
| Initial CD4 > 500/mm3 |
11 |
1 |
|
| CDC categories |
|
|
|
| A |
11 |
1 |
|
| B |
6 |
0.78(0.63-0.79) |
0.025 |
| C |
2.7 |
0.72(0.57-0.91) |
0.006 |
| Known drug use/addiction |
|
|
|
| no |
7.5 |
1 |
|
| yes |
10 |
1.80(1.20-2.80) |
0.01 |
| ARV therapy |
|
|
|
| HAART+ |
3.9 |
0.24(0.19-0.30) |
0.000 |
| HAART- |
11 |
1 |
|
*Obtained using a Cox proportional hazard model including all the above mentioned
covariates.
CI: confidence interval; py: person-years |