Figure 4: Thirty days of AZT treatment results in an increase in mutations in the mitochondrial genome. The number of shifts, and therefore mutations, by amplicon, observed for the HepG2 (A) and CCD-1112Sk (B) cell lines after thirty days of AZT treatment. The combined results for all replicates for each experiment are in black for the AZT treated samples, and are in white for the non-AZT treated. A * represents those samples that have a p-value of 0.05 or less.