Treatment

Amplicon

Mutation

AZT Treated

HV2

11A
24A
64T
80A
128C – 382A – 396C
181A
198G
295A
320A – 345A
369A – 382C – 388A
369A – 388A
382A – 396C
388A

CO2

7830G
7918T – 7966T – 8117T
7982C
7982C– 8019T
7985T
7986G

ND1

3573A – 3632A – 3670A
3905G
3993C

Non-AZT Treated

HV2

79C
181A
186A-253A-296C
238A
295A
320A – 345A
331A
345A
388A

CO2

7718A
7931C – 7982C
7985T
8087G
8206T

ND1

3847G
3941A
3947A
4001T

Each line is a different sample. Instances of more than one mutation in a sequence are indicated by a hyphen between mutations.
Table 3: Representative mutations found in randomly selected treated and untreated samples with signature shifts for all three amplicons.