Figure 1: Study outline.
Antiretroviral treatment (ART) throughout the study is indicated at the top for both study arms. For the ART group, the schedule included two treatment interruptions of 4 and 12 weeks, respectively, separated by 14 weeks on ART. Periods with treatment are shown in white boxes marked ‘ART’, and periods without treatment are in shaded boxes marked ‘NO ART’. Immunization periods are indicated with arrows.
Immunizations were given in two blocks at 11 different time-points: The prime immunization at weeks 1 (3 injections), 2 (2 injections), 3, 4, and 6, and booster immunizations at weeks 24, 25, and 26.
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