|
| Figure 3: Scheme of molecular imprinting against gp120. Gp120 receptors are chosen as the target and imprint molecule for this hypothesis. First step is to consider the gp120 monomers and template (template is a constant, short peptide sequence illustrative of an available fragment of a larger protein, holes on the template are representative of the active sites on the gp120 template). Afterwards, all elements of the MIPs are combined and allowed to be self-assembled to form the cross-linked polymer with the template (prepolymerization). After polymerization, monomers and the surrounding matrix are cleaved from the template molecules. The resulting targeted MIPs will be able selectively to bind to gp120. |
